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KMID : 0043320120350030461
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Archives of Pharmacal Research
2012 Volume.35 No. 3 p.461 ~ p.468
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Tetrahydroanthraquinone and xanthone derivatives from the marine-derived fungus Trichoderma aureoviride PSU-F95
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Khamthong Nanthaphong
Rukachaisirikul Vatcharin
Tadpetch Kwanruthai
Kaewpet Morakot
Phongpaichit Souwalak
Preedano Sita
Preedanon Sita
Sakayaroj Jariya
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Abstract
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Trichodermaquinone (1) and trichodermaxanthone (2) were isolated from the marine-derived fungus Trichoderma aureoviride PSU-F95 together with eleven known compounds. The structures were interpreted by spectroscopic methods. Known coniothranthraquinone 1 and emodin displayed strong antibacterial activity against methicillin-resistant Staphylococcus aureus with the MIC values of 8 and 4 μg/mL, respectively.
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KEYWORD
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Trichoderma aureoviride, Marine-derived fungus, Tetrahydroanthraquinone, Xanthone, Antibacterial activity
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